Ringer’s Solution, Sterile (Physiological Salt Solution) BZ211
Product Code: BZ211
Manufacturer: Biochemazone
Available Pack Sizes: 100 mL, 200 mL, 500 mL, 1 L
Custom Bulk Quantities Available
Product Overview
Biochemazone Ringer’s Solution BZ211 is a sterile, isotonic physiological salt solution of sodium chloride, potassium chloride and calcium chloride in high-purity water. It follows the classic Ringer formulation and keeps isolated tissues, organs and cells bathed in the main extracellular ions they need.
The solution is named after the physiologist Sydney Ringer, who showed in the 1880s that a beating heart needs sodium, potassium and calcium in a fixed balance. Today Ringer’s solution is used to rinse and hold tissues, keep organ-bath and muscle preparations alive, and as a balanced, isotonic diluent. It is sterile-filtered through a 0.2 µm membrane.
Each batch is prepared with ISO 3696 compliant high-purity water under Biochemazone’s ISO 9001 / GMP quality system.
Key Features & Benefits
✅ Classic Ringer Formulation – Na+, K+, Ca2+ and Cl−
✅ Isotonic – About 309 mOsm/L (calculated)
✅ Sterile-Filtered – 0.2 µm membrane filtration
✅ Ready to Use – No dilution or mixing needed
✅ Tissue-Friendly – Keeps isolated tissues and organs viable
✅ 100 mL to 1 L – Plus custom bulk volumes
✅ ISO 3696 Grade Water – Prepared using high-purity laboratory water
✅ Made in Canada – Manufactured under ISO 9001 / GMP quality systems
Applications
🫀 Physiology & Pharmacology
• Isolated heart, smooth-muscle and skeletal-muscle preparations
• Organ-bath and tissue-holding solutions
• Teaching practicals on muscle and nerve physiology
🔬 Tissue Handling
• Rinsing and transporting freshly dissected tissue
• Isotonic diluent for cells and tissue samples
• Short-term holding of explants
🧪 General Laboratory Use
• Balanced isotonic salt solution for in vitro work
• Control and vehicle solution in research studies
Usage Areas
- Physiology and pharmacology laboratories
- Animal and veterinary research groups
- Tissue and organ research laboratories
- Biomedical and life-science R&D
- Academic and teaching laboratories
Composition (per litre)
| Component |
Concentration |
Amount per litre |
| Sodium chloride (NaCl) |
147 mM |
8.6 g |
| Potassium chloride (KCl) |
4 mM |
0.30 g |
| Calcium chloride dihydrate (CaCl2·2H2O) |
2.25 mM |
0.33 g |
| High-purity water (ISO 3696) |
— |
to 1 L |
Classic Ringer formulation: Na+ 147 mM, K+ 4 mM, Ca2+ 2.25 mM, Cl− about 156 mM. Contains no buffer, glucose or lactate.
Typical Properties
- Appearance: Clear, colourless liquid
- pH: About 5.0–7.5 (unbuffered salt solution)
- Osmolarity: About 309 mOsm/L (calculated)
- Format: Sterile-filtered (0.2 µm)
Available Formulations
- Ringer’s solution, sterile (this product, BZ211)
- Amphibian Ringer’s and Holtfreter’s solution (BZ716)
- Tyrode’s solution (with glucose and bicarbonate) (BZ212)
- Krebs-Henseleit buffer (BZ662)
- Physiological saline solution (PHSS) (BZ474)
Storage, Shelf Life & Transportation
- Storage Temperature: 2–30 °C
- Shelf Life: 1 year for unopened bottles
- Transportation: Room temperature (ambient shipping)
- Calcium salts can form a slight precipitate – warm gently and mix; discard if a heavy precipitate remains
- After opening, handle aseptically and keep tightly closed
Customization Options
- Amphibian, avian or fish Ringer’s recipes
- Lactated Ringer’s-type and bicarbonate versions
- Added glucose or HEPES buffer
- Bulk containers
Ordering Information
BZ211 is available in standard laboratory sizes or OEM/bulk supply formats.
📄 MSDS, Technical Datasheet, and Certificate of Analysis (CoA) available upon request
Email: info@biochemazone.com
Website: www.biochemazone.com
⚠️ For laboratory research use only. Not for human or animal injection or therapeutic use.
