Rat Artificial Cerebrospinal Fluid (CSF) – Synthetic Rat CSF for Neuroscience Research, pH 7.3–7.4 BZ498
Product Code: BZ498
Manufacturer: Biochemazone
Available Pack Sizes: 100 mL, 200 mL, 500 mL, 1 L
Custom Bulk Quantities Available
Product Overview
Biochemazone Rat Artificial Cerebrospinal Fluid (CSF) BZ498 is a sterile, ready-to-use synthetic solution formulated to simulate the composition of cerebrospinal fluid in rats, at pH 7.3 to 7.4. It mimics the ionic and osmotic properties of natural rat CSF. The standard formulation contains the electrolytes sodium, potassium, calcium, magnesium, chloride, bicarbonate and phosphate, with glucose as an option, in a bicarbonate-buffered system; a HEPES-buffered version is available on request.
BZ498 is used in neuroscience, biomedical research and physiological studies: for electrophysiological recordings and neural tissue perfusion, to maintain the physiological ionic balance of rat tissue explants, organotypic cultures and brain slices, for controlled drug delivery and pharmacokinetic assays under CSF-like conditions, and for compatibility and functional testing of implants or monitoring systems that interface with the CSF. It is manufactured under strict quality control, so that experiments can be reproduced.
It is supplied stabilized and has a 1-year shelf life unopened; a preservative-free version (6-month shelf life) and a dried Powder Version Kit are available on request. Optional additives such as glucose, amino acids or pharmacological agents can be included on request. This simulated fluid is for scientific research and in vitro use only; it is not for clinical diagnosis or treatment. For mouse and dog CSF see Mouse and Dog Artificial CSF and Mouse Interstitial Fluid BZ712; for rat interstitial fluid see Synthetic Rat Interstitial Fluid BZ531.
Key Features & Benefits
✅ Physiological Relevance – Ion concentrations, pH and osmolarity characteristic of native rat CSF
✅ pH 7.3–7.4 – Bicarbonate-buffered; HEPES-buffered on request
✅ High Purity & Consistency – Strict quality control for reproducible experiments
✅ Stabilized – Contains a preservative that stops microbial growth; 1-year shelf life unopened. Preservative-free version on request
✅ Sterile & Ready to Use – No weighing, mixing or pH adjustment before the test
✅ Made in Canada – Manufactured under ISO 9001 / GMP quality systems
Applications
🧠 Neuroscience Research
• Electrophysiological recordings
• Neural tissue perfusion
🧫 Tissue & Slice Work
• Rat tissue explants and organotypic cultures
• Brain slices kept in physiological ionic balance
💊 Pharmacological Studies
• Controlled drug delivery under CSF-like conditions
• Pharmacokinetic assays
🩺 Biomedical Device Testing
• Compatibility testing of implants
• Functional testing of monitoring systems that interface with the CSF
Typical Properties
- pH: 7.3 to 7.4 (customizable)
- Electrolytes: Sodium (Na⁺), potassium (K⁺), calcium (Ca²⁺), magnesium (Mg²⁺), chloride (Cl⁻), bicarbonate (HCO₃⁻), phosphate
- Osmolyte: Glucose (optional)
- Buffer system: Bicarbonate; HEPES-buffered on request
- Format: Sterile, ready-to-use liquid, stabilized
Storage, Shelf Life & Transportation
- Storage Temperature: 2–30 °C, protected from light
- Transportation: At room temperature
- Shelf Life: 1 year (unopened)
- Preservative-Free Version: Available on request – shelf life 6 months unopened at 2–30 °C
- Powder Version Kit: Available on request – 2-year shelf life, easy to reconstitute and suitable for culture-related applications; recommended when a preservative is not required
- After Opening: Handle aseptically; close tightly after use and do not return unused material to the container
Customization Options
Customization available on request:
- pH adjustment to the project requirement
- Glucose, amino acids or pharmacological agents added on request
- HEPES-buffered version
- Preservative-free (not-stabilized) version
- Powder Version Kit, custom pack sizes and bulk carboys (5 L, 10 L, 20 L)
Frequently Asked Questions
What does BZ498 contain?
The electrolytes sodium, potassium, calcium, magnesium, chloride, bicarbonate and phosphate at pH 7.3 to 7.4, with glucose as an option. A HEPES-buffered version and other additives are available on request.
How long does the solution keep?
Unopened, the stabilized solution has a 1-year shelf life at 2–30 °C. A preservative-free version with a 6-month shelf life and a dried Powder Version Kit with a 2-year shelf life are available on request.
Ordering Information
BZ498 is available in standard laboratory sizes or OEM/bulk supply formats.
📄 MSDS, Technical Datasheet, and Certificate of Analysis (CoA) available upon request
📧 Email: info@biochemazone.com
🌐 Website: www.biochemazone.com
⚠️ For research, education, and in vitro testing only. Not for human or animal use.
