Simulated Duodenal Fluid – Artificial Duodenal Fluid for Pharmacokinetic Research, pH 6.0–6.5 BZ299
Product Code: BZ299
Manufacturer: Biochemazone
Available Pack Sizes: 100 mL, 200 mL, 500 mL, 1 L
Custom Bulk Quantities Available
Product Overview
Biochemazone Simulated Duodenal Fluid BZ299, also called artificial duodenal fluid, is a sterile, ready-to-use solution that simulates the composition and pH of the fluid of the duodenum, at pH 6.0 to 6.5. It contains inorganic elements, bicarbonate and the enzyme lipase.
The duodenum is the first part of the small intestine, where the contents of the stomach meet bile and pancreatic juice. Simulated stomach and duodenum fluids are used to study the effect of fluid volume on a drug and its pharmacokinetics. BZ299 is not a drug and is not for in vivo use.
It is supplied stabilized and has a 1-year shelf life unopened; a preservative-free version (6-month shelf life) and a dried Powder Version Kit are available on request. Because it contains enzymes, keep it at 2–8 °C if it is to be stored for a long time. The pH and the contents can be customized to the project. This simulated fluid is for scientific research and in vitro use only; it is not for clinical diagnosis or treatment. For the fluids that enter the duodenum see Simulated Bile Juice (BZ263) and Simulated Pancreatic Juice (BZ271).
Key Features & Benefits
✅ Simulates Duodenal Fluid – Inorganic elements, bicarbonate and lipase
✅ pH 6.0–6.5 – Customizable to the project requirement
✅ Non-Human – The same composition in every batch
✅ Stabilized – Contains a preservative that stops microbial growth; 1-year shelf life unopened. Preservative-free version on request
✅ Sterile & Ready to Use – No weighing, mixing or pH adjustment before the test
✅ Reproducible & Standardized – Consistent batch-to-batch composition for routine QC and inter-laboratory comparison
✅ Made in Canada – Manufactured under ISO 9001 / GMP quality systems
Applications
💊 Pharmacokinetic Research
• Effect of fluid volume on a drug
• Behaviour of drugs and formulations in the upper small intestine
🔬 In Vitro Research
• Stand-in for duodenal fluid in laboratory studies
• Comparison between batches and laboratories
Typical Properties
- Appearance: Clear solution
- pH: 6.0–6.5 (customizable)
- Composition: Inorganic elements, bicarbonate and lipase; contents customizable
- Format: Sterile, ready-to-use liquid, stabilized
Storage, Shelf Life & Transportation
- Storage Temperature: 2–30 °C, protected from light
- Transportation: At room temperature
- Shelf Life: 1 year (unopened)
- Preservative-Free Version: Available on request – shelf life 6 months unopened at 2–30 °C
- Enzyme-Containing Product: Best kept at 2–8 °C for prolonged storage and activity; storage at 2–30 °C is fine for short-term use
- Powder Version Kit: Available on request – 2-year shelf life, easy to reconstitute and suitable for culture-related applications; recommended when a preservative is not required
- After Opening: Handle aseptically; close tightly after use and do not return unused material to the container
Customization Options
Customization available on request:
- pH adjustment to the project requirement
- Contents to your specification
- Preservative-free (not-stabilized) version
- Powder Version Kit, custom pack sizes and bulk carboys (5 L, 10 L, 20 L)
Frequently Asked Questions
What does BZ299 contain?
Inorganic elements, bicarbonate and the enzyme lipase, at pH 6.0 to 6.5.
How should it be stored?
Store it at 2–30 °C; because it contains enzymes, 2–8 °C is best for prolonged storage and to keep the enzymes active. It is shipped at room temperature. Unopened, the stabilized solution has a 1-year shelf life; a preservative-free version with a 6-month shelf life and a dried Powder Version Kit with a 2-year shelf life are available on request.
Ordering Information
BZ299 is available in standard laboratory sizes or OEM/bulk supply formats.
📄 MSDS, Technical Datasheet, and Certificate of Analysis (CoA) available upon request
📧 Email: info@biochemazone.com
🌐 Website: www.biochemazone.com
⚠️ For research, education, and in vitro testing only. Not for human or animal use.
