Simulated Urine with High Protein Load – Proteinuric Urine Simulant, pH 6.0 BZ542
Product Code: BZ542
Manufacturer: Biochemazone
Available Pack Sizes: 100 mL, 200 mL, 500 mL, 1 L
Custom Bulk Quantities Available
Product Overview
Biochemazone Simulated Urine with High Protein Load BZ542 is a laboratory-formulated urine simulant that replicates the physicochemical properties of human urine under proteinuric conditions. It is a buffered aqueous solution of electrolytes and protein analogs at pH 6.0, with the ionic composition of urine and the elevated protein content seen in proteinuria, kidney dysfunction and urinary tract disorders. It is clear to slightly opalescent, enzyme-free and non-biological.
BZ542 is used for in vitro diagnostic development and renal biomarker research, for the calibration of urinary sensors and the testing of urine analysis systems, for evaluating catheters and urological devices under protein-rich conditions, for filtration and dialysis membrane studies, and for fouling and coating-resistance tests. It lets a study be repeated at a controlled protein concentration, which patient urine cannot offer.
It is supplied stabilized, with 0.05% preservative, and has a 1-year shelf life unopened; a preservative-free version (6-month shelf life) and a dried Powder Version Kit are available on request. Because it contains protein analogs, keep it at 2–8 °C if it is to be stored for a long time. The protein concentration can be set from low to the nephrotic range, and the pH and ionic strength can be adjusted. For research, education and in vitro testing only. For a milder proteinuria urine see Simulated Proteinuria Urine BZ399; for the normal urine see Artificial Human Urine BZ340.
Key Features & Benefits
✅ High Protein Load – Controlled protein analogs replicate proteinuric conditions
✅ pH 6.0 – Adjustable within the urinary range, about 5.5 to 7.5
✅ Non-Biological – Free from pathogens and biological contaminants; enzyme-free
✅ Stabilized – 0.05% preservative stops microbial growth; 1-year shelf life unopened. Preservative-free version on request
✅ Ready to Use – No weighing, mixing or pH adjustment before the test
✅ Reproducible & Standardized – Consistent batch-to-batch composition for routine QC and inter-laboratory comparison
✅ Made in Canada – Manufactured under ISO 9001 / GMP quality systems
Applications
🧪 Renal & Diagnostic Research
• Proteinuria and kidney dysfunction simulation
• Biomarker detection and assay development
• Urinary protein interaction studies
🩺 Medical Device Testing
• Urine analysis systems
• Catheters and urological devices in protein-rich urine
• Sensor calibration
💊 Pharmaceutical & Biochemical Studies
• Drug–protein interaction in urine
• Precipitation and aggregation behaviour
• Formulation stability in protein-rich urine
🧱 Material Compatibility
• Fouling of membranes and polymers
• Coating resistance
• Filtration and dialysis membrane performance
Typical Properties
- Appearance: Clear to slightly opalescent solution
- pH: 6.0 (adjustable, about 5.5–7.5)
- Protein content: Elevated – simulated proteinuric range; customizable
- Composition: Buffered aqueous solution with electrolytes and protein analogs; 0.05% preservative
- Enzymes: Enzyme-free (enzymes can be added on request)
- Format: Ready-to-use liquid, stabilized
Storage, Shelf Life & Transportation
- Storage Temperature: 2–30 °C, protected from light
- Transportation: At room temperature
- Shelf Life: 1 year (unopened)
- Preservative-Free Version: Available on request – shelf life 6 months unopened at 2–30 °C
- Protein-Containing Product: Best kept at 2–8 °C for prolonged storage and stability; storage at 2–30 °C is fine for short-term use
- Powder Version Kit: Available on request – 2-year shelf life, easy to reconstitute and suitable for culture-related applications; recommended when a preservative is not required
- After Opening: Handle aseptically; close tightly after use and do not return unused material to the container
Customization Options
Customization available on request:
- Protein concentration from low to the nephrotic range
- pH and ionic strength
- Biomarkers or organic components added
- Preservative-free (not-stabilized) version
- Powder Version Kit, custom pack sizes and bulk carboys (5 L, 10 L, 20 L)
Frequently Asked Questions
How does BZ542 differ from BZ399?
Both are urines with protein. BZ542 has a high protein load, adjustable up to the nephrotic range, for membrane, fouling and device studies; Simulated Proteinuria Urine BZ399 is the standard proteinuria urine for test strips and quality control.
How should BZ542 be stored?
Store it at 2–30 °C; for prolonged storage, 2–8 °C is best because it contains protein analogs. It is shipped at room temperature. Unopened, the stabilized solution has a 1-year shelf life; a preservative-free version with a 6-month shelf life is available on request.
Ordering Information
BZ542 is available in standard laboratory sizes or OEM/bulk supply formats.
📄 MSDS, Technical Datasheet, and Certificate of Analysis (CoA) available upon request
📧 Email: info@biochemazone.com
🌐 Website: www.biochemazone.com
⚠️ For research, education, and in vitro testing only. Not for human or animal use.
