Artificial Cerebrospinal Interstitial Fluid – Synthetic Fluid of the Central Nervous System for Neuroscience Research, pH 7.3 BZ453
Product Code: BZ453
Manufacturer: Biochemazone
Available Pack Sizes: 100 mL, 200 mL, 500 mL, 1 L
Custom Bulk Quantities Available
Product Overview
Biochemazone Artificial Cerebrospinal Interstitial Fluid BZ453, also called simulated cerebrospinal interstitial fluid, is a ready-to-use synthetic solution designed to replicate the properties of natural cerebrospinal interstitial fluid, at pH 7.3. It contains water, electrolytes and biomolecules, which mimic the physical and chemical characteristics of the natural fluid. The pH of natural cerebrospinal interstitial fluid is about 7.31 to 7.41; the standard formulation is set at 7.3. Its viscosity and density are matched to the natural fluid, and it stays stable through the test.
Research laboratories use it to study the interactions between cerebrospinal interstitial fluid and neural tissues, including nutrient transport, waste removal and fluid balance, and in assays that study neural biomarkers. It is also used to test and calibrate medical devices that interact with cerebrospinal fluids, such as diagnostic tools for brain and spinal assessment and equipment that measures cerebrospinal fluid pressure, flow and composition, in research on neuroscience and cerebrospinal fluid dynamics, and in training in neurology and neurosurgery, without the need for actual cerebrospinal fluids.
It is supplied stabilized and has a 1-year shelf life unopened; a preservative-free version (6-month shelf life) and a dried Powder Version Kit are available on request. The formulation, minerals, organic content and pH can be customized. This simulated fluid is for scientific research and in vitro use only; it is not for clinical diagnosis or treatment. For the cerebrospinal fluid see Artificial Cerebrospinal Solution (ACSF, Sterile) (BZ178); for the brain interstitium see Artificial Cerebral Interstitial Fluid (BZ418); for the glymphatic fluid see Artificial Glymphatic Fluid (BZ442).
Key Features & Benefits
✅ Replicates Natural cerebrospinal interstitial fluid – Water, electrolytes and biomolecules
✅ pH 7.3 – Natural range about 7.31 to 7.41; customizable
✅ Matched Properties – Viscosity, density and pH close to the natural fluid
✅ Stabilized – Contains a preservative that stops microbial growth; 1-year shelf life unopened. Preservative-free version on request
✅ Ready to Use – No weighing, mixing or pH adjustment before the test
✅ Reproducible & Standardized – Consistent batch-to-batch composition for routine QC and inter-laboratory comparison
✅ Made in Canada – Manufactured under ISO 9001 / GMP quality systems
Applications
🧠 Neuroscience Research
• Nutrient transport, waste removal and fluid balance in neural tissue
• Neural biomarker assays
🩺 Device Testing & Calibration
• Diagnostic tools for brain and spinal assessment
• Equipment that measures cerebrospinal fluid pressure, flow and composition
🎓 Research, Training & Education
• Research on cerebrospinal fluid dynamics
• Training in neurology and neurosurgery without actual cerebrospinal fluids
Typical Properties
- pH: 7.3 (natural range about 7.31 to 7.41; customizable)
- Composition: Water, electrolytes and biomolecules
- Viscosity and density: Matched to the natural fluid
- Format: Ready-to-use liquid, stabilized
Storage, Shelf Life & Transportation
- Storage Temperature: 2–30 °C, protected from light
- Transportation: At room temperature
- Shelf Life: 1 year (unopened)
- Preservative-Free Version: Available on request – shelf life 6 months unopened at 2–30 °C
- Powder Version Kit: Available on request – 2-year shelf life, easy to reconstitute and suitable for culture-related applications; recommended when a preservative is not required
- After Opening: Handle aseptically; close tightly after use and do not return unused material to the container
Customization Options
Customization available on request:
- pH adjustment to the project requirement
- Formulation, minerals and organic content
- Preservative-free (not-stabilized) version
- Powder Version Kit, custom pack sizes and bulk carboys (5 L, 10 L, 20 L)
Frequently Asked Questions
What does BZ453 contain?
Water, electrolytes and biomolecules, at pH 7.3, with a viscosity and density matched to natural cerebrospinal interstitial fluid.
How long does the solution keep?
Unopened, the stabilized solution has a 1-year shelf life at 2–30 °C. A preservative-free version with a 6-month shelf life and a dried Powder Version Kit with a 2-year shelf life are available on request.
Ordering Information
BZ453 is available in standard laboratory sizes or OEM/bulk supply formats.
📄 MSDS, Technical Datasheet, and Certificate of Analysis (CoA) available upon request
📧 Email: info@biochemazone.com
🌐 Website: www.biochemazone.com
⚠️ For research, education, and in vitro testing only. Not for human or animal use.
