Simulated Epidural Fluid – Synthetic Epidural Fluid for Spinal Research and Device Testing, pH 7.4 BZ441
Product Code: BZ441
Manufacturer: Biochemazone
Available Pack Sizes: 100 mL, 200 mL, 500 mL, 1 L
Custom Bulk Quantities Available
Product Overview
Biochemazone Simulated Epidural Fluid BZ441, also called artificial epidural fluid, is a ready-to-use synthetic solution designed to replicate the properties of natural epidural fluid, at pH 7.4. It contains water, electrolytes, proteins and other relevant compounds, which mimic the physical and chemical characteristics of the natural fluid. The pH of natural epidural fluid is about 7.3 to 7.4; the standard formulation is set at 7.4. Its viscosity and density are matched to the natural fluid, and it stays stable through the test.
Research laboratories use it to study the interaction between epidural fluid and the surrounding environment, including its role in spinal health and drug delivery systems, and in tests that measure biomarkers in the epidural space. It is also used to test and calibrate medical devices that interact with epidural fluid, such as spinal needles, catheters and drug delivery systems, in the development of new technologies and procedures in spinal anesthesia, pain management and neurology, and in training, without the need for human epidural fluid.
It is supplied stabilized and has a 1-year shelf life unopened; a preservative-free version (6-month shelf life) and a dried Powder Version Kit are available on request. Because it contains protein, keep it at 2–8 °C if it is to be stored for a long time. The formulation, minerals, organic content and pH can be customized. This simulated fluid is for scientific research and in vitro use only; it is not for clinical diagnosis or treatment. For the subdural space see Artificial Subdural Fluid (BZ449); for the cerebrospinal fluid see Artificial Cerebrospinal Solution (ACSF, Sterile) (BZ178).
Key Features & Benefits
✅ Replicates Natural epidural fluid – Water, electrolytes, proteins and other relevant compounds
✅ pH 7.4 – Natural range about 7.3 to 7.4; customizable
✅ Matched Properties – Viscosity, density and pH close to the natural fluid
✅ Stabilized – Contains a preservative that stops microbial growth; 1-year shelf life unopened. Preservative-free version on request
✅ Ready to Use – No weighing, mixing or pH adjustment before the test
✅ Reproducible & Standardized – Consistent batch-to-batch composition for routine QC and inter-laboratory comparison
✅ Made in Canada – Manufactured under ISO 9001 / GMP quality systems
Applications
🔬 Spinal Research
• Role of epidural fluid in spinal health and drug delivery
• Biomarker measurement in the epidural space
🩺 Device Testing & Calibration
• Spinal needles and catheters
• Drug delivery systems
🎓 Research, Training & Education
• New technologies and procedures in spinal anesthesia, pain management and neurology
• Practice of procedures without human epidural fluid
Typical Properties
- pH: 7.4 (natural range about 7.3 to 7.4; customizable)
- Composition: Water, electrolytes, proteins and other relevant compounds
- Viscosity and density: Matched to the natural fluid
- Format: Ready-to-use liquid, stabilized
Storage, Shelf Life & Transportation
- Storage Temperature: 2–30 °C, protected from light
- Transportation: At room temperature
- Shelf Life: 1 year (unopened)
- Preservative-Free Version: Available on request – shelf life 6 months unopened at 2–30 °C
- Protein-Containing Product: Best kept at 2–8 °C for prolonged storage and stability; storage at 2–30 °C is fine for short-term use
- Powder Version Kit: Available on request – 2-year shelf life, easy to reconstitute and suitable for culture-related applications; recommended when a preservative is not required
- After Opening: Handle aseptically; close tightly after use and do not return unused material to the container
Customization Options
Customization available on request:
- pH adjustment to the project requirement
- Formulation, minerals and organic content
- Preservative-free (not-stabilized) version
- Powder Version Kit, custom pack sizes and bulk carboys (5 L, 10 L, 20 L)
Frequently Asked Questions
What does BZ441 contain?
Water, electrolytes, proteins and other relevant compounds, at pH 7.4, with a viscosity and density matched to natural epidural fluid.
How should it be stored?
Store it at 2–30 °C; because it contains protein, 2–8 °C is best for prolonged storage. It is shipped at room temperature. Unopened, the stabilized solution has a 1-year shelf life; a preservative-free version with a 6-month shelf life and a dried Powder Version Kit with a 2-year shelf life are available on request.
Ordering Information
BZ441 is available in standard laboratory sizes or OEM/bulk supply formats.
📄 MSDS, Technical Datasheet, and Certificate of Analysis (CoA) available upon request
📧 Email: info@biochemazone.com
🌐 Website: www.biochemazone.com
⚠️ For research, education, and in vitro testing only. Not for human or animal use.
