Artificial Nasal Mucus – Sterile Simulated Nasal Mucus for In Vitro Diagnostic Research, pH 6.5 BZ253
Product Code: BZ253
Manufacturer: Biochemazone
Available Pack Sizes: 100 mL, 200 mL, 500 mL, 1 L
Custom Bulk Quantities Available
Product Overview
Biochemazone Artificial Nasal Mucus BZ253, also called simulated nasal mucus fluid or simulated nasal mucus matrix, is a sterile, ready-to-use solution that simulates the composition and pH of nasal mucus. It can be used directly and is supplied at pH 6.5; the stabilizer, pH and contents can be customized.
Fluid from the nose and the nasopharynx is collected by swab, aspirate or wash. BZ253 gives laboratories a nasal mucus of constant composition for in vitro testing and diagnostic research, for example as a matrix in work on the detection of bacterial and viral pathogens, such as those of diphtheria, meningitis, pertussis, COVID-19 and pneumonia. The table below compares the typical viscosities of natural respiratory secretions, for reference.
It is supplied stabilized and has a 1-year shelf life unopened; a preservative-free version (6-month shelf life) and a dried Powder Version Kit are available on request. Because it contains protein and mucin, keep it at 2–8 °C if it is to be stored for a long time. The stabilizer, pH and contents can be customized to the project. This simulated fluid is for scientific research and in vitro use only; it is not for clinical diagnosis or treatment. For the thinner nasal fluid see Artificial Nasal Fluid (BZ251); for mucus see Artificial Mucus Matrix (BZ275); for the viscosity set see Airway Mucus Simulant Viscosity Set BZ611.
Viscosity of respiratory secretions – comparison (reference only)
| Secretion type | Typical viscosity (cP) | Notes / conditions |
|---|
| Nasal mucus (healthy, normal) | 1,000 – 10,000 | Shear-thinning, varies with hydration |
| Nasal mucus (thin / watery) | 100 – 500 | During colds, high hydration |
| Nasal mucus (thick / dehydrated) | 100,000 – 1,000,000 | Sinus infections, cystic fibrosis |
| Sputum (healthy, normal) | 100 – 2,000 | From the lower respiratory tract |
| Sputum (thick, pathological) | 10,000 – 100,000 | Chronic bronchitis, cystic fibrosis, asthma |
| Saliva (resting) | 1 – 10 | Less viscous than mucus |
| Saliva (stimulated) | 0.5 – 5 | After chewing or citric stimulation |
| Tear fluid | 1 – 10 | Mostly watery, low viscosity |
| Bronchial mucus (normal) | 1,000 – 2,000 | Lubricates the airway, shear-thinning |
Most respiratory secretions are non-Newtonian: their viscosity falls under shear, for example when the nose is blown or on coughing. Viscosity can rise sharply during infection, dehydration or diseases such as cystic fibrosis.
Key Features & Benefits
✅ Simulates Nasal Mucus – Composition and pH of the mucus of the nose
✅ pH 6.5 – Customizable to the project requirement
✅ Matrix for Pathogen Detection Work – In vitro research on tests for COVID-19, pertussis, pneumonia and other respiratory pathogens
✅ Stabilized – Contains a preservative that stops microbial growth; 1-year shelf life unopened. Preservative-free version on request
✅ Sterile & Ready to Use – No weighing, mixing or pH adjustment before the test
✅ Reproducible & Standardized – Consistent batch-to-batch composition for routine QC and inter-laboratory comparison
✅ Made in Canada – Manufactured under ISO 9001 / GMP quality systems
Applications
🧪 Diagnostic Research
• Matrix for in vitro work on the detection of bacterial and viral pathogens, including COVID-19 (SARS-CoV-2)
• Stand-in for samples collected by swab, aspirate or wash
🔬 In Vitro Laboratory Research
• Studies that need a nasal mucus of constant composition
• Reproducible test matrix
Typical Properties
- pH: 6.5 (customizable)
- Composition: Formulated to simulate the composition of nasal mucus; contains protein and mucin
- Format: Sterile, ready-to-use liquid, stabilized
Storage, Shelf Life & Transportation
- Storage Temperature: 2–30 °C, protected from light
- Transportation: At room temperature
- Shelf Life: 1 year (unopened)
- Preservative-Free Version: Available on request – shelf life 6 months unopened at 2–30 °C
- Protein- and Mucin-Containing Product: Best kept at 2–8 °C for prolonged storage and stability; storage at 2–30 °C is fine for short-term use
- Powder Version Kit: Available on request – 2-year shelf life, easy to reconstitute and suitable for culture-related applications; recommended when a preservative is not required
- After Opening: Handle aseptically; close tightly after use and do not return unused material to the container
Customization Options
Customization available on request:
- pH adjustment to the project requirement
- Contents to your specification
- Preservative-free (not-stabilized) version
- Powder Version Kit, custom pack sizes and bulk carboys (5 L, 10 L, 20 L)
Frequently Asked Questions
How viscous is natural nasal mucus?
Healthy nasal mucus is typically 1,000 to 10,000 cP and shear-thinning. Thin, watery mucus during a cold is about 100 to 500 cP, and thick, dehydrated mucus can reach 100,000 to 1,000,000 cP. These are reference values for natural secretions.
How should it be stored?
Store it at 2–30 °C; because it contains protein and mucin, 2–8 °C is best for prolonged storage. It is shipped at room temperature. Unopened, the stabilized solution has a 1-year shelf life; a preservative-free version with a 6-month shelf life and a dried Powder Version Kit with a 2-year shelf life are available on request.
Ordering Information
BZ253 is available in standard laboratory sizes or OEM/bulk supply formats.
📄 MSDS, Technical Datasheet, and Certificate of Analysis (CoA) available upon request
📧 Email: info@biochemazone.com
🌐 Website: www.biochemazone.com
⚠️ For research, education, and in vitro testing only. Not for human or animal use.
