Artificial Canine Intestinal Fluid – BZ516
Product Code: BZ516
Manufacturer: Biochemazone
Available Pack Sizes: 100 mL, 200 mL, 500 mL, 1 L
Custom Bulk Quantities Available
Product Overview
Biochemazone Artificial Canine Intestinal Fluid BZ516 is a laboratory-formulated synthetic simulant that replicates the physicochemical environment of the canine small intestinal lumen. This fluid mimics the neutral to mildly alkaline pH range, electrolyte balance, and surfactant-rich composition of intestinal fluid found in dogs. Designed for in vitro testing, veterinary research, dissolution studies, and medical device evaluation, BZ516 provides a safe, reproducible, and non-biological alternative to animal-derived intestinal contents.
The formulation supports controlled experimentation in drug solubility and dissolution testing, gastrointestinal absorption studies, and digestive process simulations without the variability and ethical concerns associated with biological samples.
Key Features & Benefits
✅ Biologically Relevant pH Profile – Simulates the normal small intestinal pH seen in canine digestive tracts, optimized for research and formulation testing
✅ Reproducible & Standardized – Consistent composition eliminates variability inherent in aspirated biological fluids
✅ Non-Biological & Safe – Free from enzymes or pathogens; ideal for laboratory use
✅ Ready-to-Use – Pre-formulated and quality controlled for immediate use
✅ Customizable Options – Adjust bile salt levels, buffer components, and surfactants to match specific research conditions
Applications
🧪 Veterinary Pharmaceutical & Dissolution Testing
• In vitro solubility and dissolution testing for canine oral dosage forms
• Comparative studies for enteric coatings and drug delivery systems
• Screening formulations under simulated small intestinal conditions
🩺 Veterinary Device R&D
• Testing of ingestible sensors and GI device functionality
• Evaluation of materials exposed to intestinal-like environments
🧬 Physiological & Absorption Research
• Simulated digestion and absorption studies
• Buffering capacity and solubilization assessments for drug candidates
🔬 Surface & Material Compatibility Testing
• Assess material stability under intestinal-like pH and surfactant conditions
• Evaluate interactions between surfactants and polymers
Typical Properties
- Appearance: Clear to slightly opalescent solution
• pH: 7.0 standard; range 6.5–7.5 (reflective of the canine small intestinal environment)
• Osmolarity: Physiologically relevant for canine intestine
• Surfactant Content: Includes bile salt–like components to mimic intestinal micelles
• Composition: Buffered aqueous matrix with electrolytes and micelle-forming additives
• Enzymes: Standard formulation is enzyme-free; enzyme-supplemented versions are available on request
Storage & Stability
- Storage Temperature: 2–30 °C, protected from light
• Shelf Life: 1 year at 2–30 °C (unopened)
• Transportation: At room temperature
Customization Options
- Bile salt and phospholipid concentration adjustments
• pH tuning within physiological intestinal range
• Optional enzyme addition to mimic digestive activity
• Tailored formulations for specific dissolution or absorption studies
Ordering Information
BZ516 is available in standard laboratory sizes or in customized OEM and bulk packaging.
📄 MSDS, Technical Datasheet, and Certificate of Analysis (CoA) available upon request
📧 Email: info@biochemazone.com
🌐 Website: www.biochemazone.com
⚠️ For research, education, and veterinary product testing only. Not for administration to animals or humans.
