Artificial Nasal Fluid – Sterile Simulated Nasal Secretions for Nasal Drug Delivery, Device and Lateral Flow Testing, pH 6.5 BZ251
Product Code: BZ251
Manufacturer: Biochemazone
Available Pack Sizes: 100 mL, 200 mL, 500 mL, 1 L
Custom Bulk Quantities Available
Product Overview
Biochemazone Artificial Nasal Fluid BZ251, also called simulated nasal fluid, is a sterile, ready-to-use solution that simulates the composition and pH of human nasal secretions. It can be used directly and is supplied at pH 6.5; the stabilizer, pH and contents can be customized.
It is designed to replicate the natural composition of human nasal secretions, and it gives a reliable medium for research and testing. In pharmaceutical research it is used to test nasal drug delivery systems such as sprays, gels and inhalers, for the in vitro testing of nasal formulations and for the analysis of drug release profiles. It is used in simulators and test rigs to evaluate nasal implants, stents and other medical devices under nasal conditions, and as a model fluid in studies of the nasal cavity: infection, allergen exposure, respiratory conditions, mucociliary clearance and nasal absorption. It also gives a consistent, realistic sample for developing, validating and quality-controlling nasal lateral flow assays, for example in work on the detection of bacterial and viral pathogens, such as those of diphtheria, meningitis, pertussis, COVID-19 and pneumonia, and it is used to assess nasal hygiene products and the interaction of products with nasal fluids.
It is supplied stabilized and has a 1-year shelf life unopened; a preservative-free version (6-month shelf life) and a dried Powder Version Kit are available on request. Because it contains protein and mucin, keep it at 2–8 °C if it is to be stored for a long time. The stabilizer, pH and contents can be customized to the project. This simulated fluid is for scientific research and in vitro use only; it is not for clinical diagnosis or treatment. For nasal mucus see Artificial Nasal Mucus (BZ253); for a runny nose see Artificial Rhinorrhea (BZ295); for the nasopharynx see Artificial Nasopharyngeal Fluid (BZ252).
Key Features & Benefits
✅ Simulates Nasal Secretions – The natural composition of human nasal fluid
✅ pH 6.5 – Customizable to the project requirement
✅ Stabilized – Contains a preservative that stops microbial growth; 1-year shelf life unopened. Preservative-free version on request
✅ Sterile & Ready to Use – No weighing, mixing or pH adjustment before the test
✅ Reproducible & Standardized – Consistent batch-to-batch composition for routine QC and inter-laboratory comparison
✅ Made in Canada – Manufactured under ISO 9001 / GMP quality systems
Applications
💊 Pharmaceutical Research
• Nasal drug delivery systems: sprays, gels and inhalers
• In vitro testing of nasal formulations and drug release profiles
🩺 Medical Device Testing
• Nasal implants, stents and other medical devices
• Simulators and test rigs that mimic nasal conditions
🧪 Lateral Flow Assays
• Simulated nasal samples for the development and validation of rapid tests, such as COVID-19 tests
• Quality control of rapid diagnostic tests
🔬 Biomedical & Product Research
• Infection, allergen exposure, mucociliary clearance and nasal absorption studies
• Stability and compatibility of nasal hygiene products
Typical Properties
- pH: 6.5 (customizable)
- Composition: Formulated to simulate the composition of human nasal secretions; contains protein and mucin
- Format: Sterile, ready-to-use liquid, stabilized
Storage, Shelf Life & Transportation
- Storage Temperature: 2–30 °C, protected from light
- Transportation: At room temperature
- Shelf Life: 1 year (unopened)
- Preservative-Free Version: Available on request – shelf life 6 months unopened at 2–30 °C
- Protein- and Mucin-Containing Product: Best kept at 2–8 °C for prolonged storage and stability; storage at 2–30 °C is fine for short-term use
- Powder Version Kit: Available on request – 2-year shelf life, easy to reconstitute and suitable for culture-related applications; recommended when a preservative is not required
- After Opening: Handle aseptically; close tightly after use and do not return unused material to the container
Customization Options
Customization available on request:
- pH adjustment to the project requirement
- Contents to your specification
- Preservative-free (not-stabilized) version
- Powder Version Kit, custom pack sizes and bulk carboys (5 L, 10 L, 20 L)
Frequently Asked Questions
Can BZ251 be used for lateral flow tests?
Yes. It gives a consistent and realistic medium for developing, validating and optimizing nasal lateral flow assays, such as COVID-19 rapid tests, and for their quality control. It is a research matrix and does not itself detect or diagnose anything.
How should it be stored?
Store it at 2–30 °C; because it contains protein and mucin, 2–8 °C is best for prolonged storage. It is shipped at room temperature. Unopened, the stabilized solution has a 1-year shelf life; a preservative-free version with a 6-month shelf life and a dried Powder Version Kit with a 2-year shelf life are available on request.
Ordering Information
BZ251 is available in standard laboratory sizes or OEM/bulk supply formats.
📄 MSDS, Technical Datasheet, and Certificate of Analysis (CoA) available upon request
📧 Email: info@biochemazone.com
🌐 Website: www.biochemazone.com
⚠️ For research, education, and in vitro testing only. Not for human or animal use.
