Simulated Vaginal Fluid pH Variants (Healthy, Elevated-pH, Post-Menopausal) BZ624
Product Code: BZ624
Manufacturer: Biochemazone
Available Pack Sizes: 100 mL, 200 mL, 500 mL, 1 L per variant, or sets of three
Custom Bulk Quantities Available
Product Overview
Biochemazone Simulated Vaginal Fluid pH Variants BZ624 extend our Simulated Vaginal Fluid (SVF, BZ181) to the three vaginal conditions that matter most for product development. The base recipe follows the vaginal fluid simulant of Owen and Katz (1999), with salts, glucose, lactic and acetic acids, glycerol, urea, albumin and mucin.
The healthy variant has a pH of 4.2, maintained by lactic acid from the normal vaginal flora. The elevated-pH variant at pH 5.5 represents the higher pH seen with bacterial vaginosis and other disturbances of the flora. The post-menopausal variant at pH 6.5 has less glycogen-derived acid and lower buffering, as after oestrogen levels fall. Products that release drugs, change pH or rely on probiotics can behave very differently across these conditions.
Each batch is prepared with ISO 3696 compliant high-purity water under Biochemazone’s ISO 9001 / GMP quality system. The mucin and albumin are of animal origin.
Key Features & Benefits
✅ Three Vaginal Conditions – Healthy, elevated-pH and post-menopausal
✅ pH 4.2, 5.5 and 6.5 – Set and checked for each variant
✅ Owen & Katz (1999) Basis – Established vaginal fluid simulant recipe
✅ Mucin and Albumin – Realistic protein and viscosity
✅ Single Variants or Sets – Buy one or all three
✅ Consistent Batch-to-Batch – Repeatable release and compatibility studies
✅ ISO 3696 Grade Water – Prepared using high-purity laboratory water
✅ Made in Canada – Manufactured under ISO 9001 / GMP quality systems
Applications
💊 Vaginal Drug Delivery
• Release from gels, rings, films and suppositories
• Microbicide and contraceptive formulation testing
• pH-responsive delivery systems
🧴 Feminine-Care Products
• pH-balancing washes and moisturisers
• Lubricant compatibility and osmolality studies
• Menopause-care product development
🦠 Microbiology & Diagnostics
• Lactobacillus and probiotic survival
• Vaginal pH-test and diagnostic development
• Bacterial vaginosis research models
Usage Areas
- Women’s-health pharmaceutical companies
- Feminine-care product manufacturers
- Probiotic and microbiome companies
- Diagnostics developers
- Universities and research institutes
Typical Properties
- Appearance: Slightly viscous, clear to opalescent liquid
- pH: healthy 4.2; elevated 5.5; post-menopausal 6.5
- Composition: Salts, glucose, lactic and acetic acids, glycerol, urea, albumin and mucin (Owen & Katz basis)
- Water Grade: ISO 3696 purified water
Storage & Stability
- Storage Temperature: 2–30 °C
- Shelf Life: 1 year for unopened bottles
- Shipping: Room temperature
- Best kept at 2–8 °C for prolonged storage and stability of the albumin and mucin components; storage at 2–30 °C is fine for short-term use
- Mix gently before use
Customization Options
- Other pH values
- Semen-containing mixtures
- Added hydrogen peroxide or amines (BV odour markers)
- Custom pack sizes and bulk supply
Ordering Information
BZ624 is available in standard laboratory sizes or OEM/bulk supply formats.
📄 MSDS, Technical Datasheet, and Certificate of Analysis (CoA) available upon request
📧 Email: info@biochemazone.com
🌐 Website: www.biochemazone.com
⚠️ For research use only. Not for human or animal use.
