Simulated Interstitial Fluid – Artificial Interstitial Fluid for In Vitro Research, pH 7.4 BZ254
Product Code: BZ254
Manufacturer: Biochemazone
Available Pack Sizes: 100 mL, 200 mL, 500 mL, 1 L
Custom Bulk Quantities Available
Product Overview
Biochemazone Simulated Interstitial Fluid BZ254, also called artificial interstitial fluid or tissue fluid, is a sterile, ready-to-use solution that simulates the composition and pH of interstitial fluid. It is supplied at pH 7.4, and the stabilizer, pH and composition can be adjusted to the project requirement.
Interstitial fluid is the thin layer of fluid that surrounds the body’s cells. It comes from substances that leak out of the blood capillaries, brings oxygen and nutrients to the cells and removes their waste products, and drains towards the lymph vessels, where it is called lymph. It contains glucose, salt, fatty acids and minerals such as calcium, magnesium and potassium, and it makes up almost 40% of the water in the body. Interstitial fluid has become important in diabetes monitoring: a continuous glucose monitor (CGM) reads the glucose level in the interstitial fluid through a small sensor placed just under the skin. BZ254 gives laboratories an interstitial fluid of constant composition for in vitro research, in place of a fluid that is very difficult to collect.
It is supplied stabilized and has a 1-year shelf life unopened; a preservative-free version (6-month shelf life) and a dried Powder Version Kit are available on request. The formulation, minerals, organic content and pH can be customized. This simulated fluid is for scientific research and in vitro use only; it is not for clinical diagnosis or treatment. For glucose levels see Interstitial Fluid Glucose Panel BZ582; for skin see Artificial Interstitial Dermal Fluid (BZ428); for the subcutaneous tissue see Simulated Subcutaneous Interstitial Fluid.
Key Features & Benefits
✅ Simulates Interstitial Fluid – The tissue fluid that surrounds the body’s cells
✅ pH 7.4 – Customizable to the project requirement
✅ Stabilized – Contains a preservative that stops microbial growth; 1-year shelf life unopened. Preservative-free version on request
✅ Sterile & Ready to Use – No weighing, mixing or pH adjustment before the test
✅ Reproducible & Standardized – Consistent batch-to-batch composition for routine QC and inter-laboratory comparison
✅ Made in Canada – Manufactured under ISO 9001 / GMP quality systems
Applications
🔬 In Vitro Research
• Studies that need an interstitial fluid of constant composition
• Replacement for a fluid that is difficult to collect
📟 Glucose-Monitoring Research
• Background matrix for work on continuous glucose monitoring
• Studies of glucose in interstitial fluid
🧪 Laboratory Testing
• In vitro testing and diagnostic research
• Reproducible test matrix
Typical Properties
- pH: 7.4 (customizable)
- Composition: Formulated to simulate the composition of interstitial fluid
- Format: Sterile, ready-to-use liquid, stabilized
Storage, Shelf Life & Transportation
- Storage Temperature: 2–30 °C, protected from light
- Transportation: At room temperature
- Shelf Life: 1 year (unopened)
- Preservative-Free Version: Available on request – shelf life 6 months unopened at 2–30 °C
- Powder Version Kit: Available on request – 2-year shelf life, easy to reconstitute and suitable for culture-related applications; recommended when a preservative is not required
- After Opening: Handle aseptically; close tightly after use and do not return unused material to the container
Customization Options
Customization available on request:
- pH adjustment to the project requirement
- Formulation, minerals and organic content
- Preservative-free (not-stabilized) version
- Powder Version Kit, custom pack sizes and bulk carboys (5 L, 10 L, 20 L)
Frequently Asked Questions
Why is interstitial fluid used in glucose monitoring?
A continuous glucose monitor measures glucose in the interstitial fluid under the skin, not in blood. Glucose in interstitial fluid follows blood glucose with a delay of around 10 minutes, so the monitor applies a formula to estimate the blood value.
How long does the solution keep?
Unopened, the stabilized solution has a 1-year shelf life at 2–30 °C. A preservative-free version with a 6-month shelf life and a dried Powder Version Kit with a 2-year shelf life are available on request.
Ordering Information
BZ254 is available in standard laboratory sizes or OEM/bulk supply formats.
📄 MSDS, Technical Datasheet, and Certificate of Analysis (CoA) available upon request
📧 Email: info@biochemazone.com
🌐 Website: www.biochemazone.com
⚠️ For research, education, and in vitro testing only. Not for human or animal use.
