Simulated Minipig and Porcine Plasma, Serum and Urine (Surrogate Bioanalysis Matrices) BZ697
Product Code: BZ697
Manufacturer: Biochemazone
Available Pack Sizes: 100 mL, 200 mL, 500 mL, 1 L
Custom Bulk Quantities Available
Product Overview
Biochemazone Simulated Minipig and Porcine Matrices BZ697 are analyte-free surrogate matrices for bioanalytical methods used in pig and minipig studies. Real porcine plasma and urine vary from animal to animal and contain endogenous compounds; a defined simulant gives a blank background for calibration standards, method development and dilution work.
Three matrices are offered. The simulated plasma and simulated serum contain albumin and electrolytes at levels based on published porcine reference ranges, in a buffered base with a pH of 7.4 ± 0.2; the plasma version also contains K2EDTA, the anticoagulant commonly used for collected plasma. The simulated urine contains urea, creatinine and salts and has a pH of about 6.5 (range 6.0–7.0). The albumin is of bovine origin.
A surrogate matrix must be shown to behave like the real matrix in your own method validation; see ICH M10 for the approaches used for endogenous analytes. Contact us for the composition details you need for your validation file. Each batch is prepared with ISO 3696 compliant high-purity water under Biochemazone’s ISO 9001 / GMP quality system.
Key Features & Benefits
✅ Plasma, Serum and Urine – Minipig and porcine studies
✅ Analyte-Free – Blank background for calibrators
✅ Plasma pH 7.4 ± 0.2 – Urine pH about 6.5
✅ Porcine Reference Ranges – Albumin and electrolyte levels
✅ K2EDTA Plasma Version – Matches collected plasma
✅ Consistent Batch-to-Batch – No animal-to-animal variation
✅ ISO 3696 Grade Water – Prepared using high-purity laboratory water
✅ Made in Canada – Manufactured under ISO 9001 / GMP quality systems
Applications
🧪 Bioanalysis
• Calibration standards and QCs
• Endogenous-analyte methods
• Dilution of high-concentration samples
🐖 Preclinical Studies
• Minipig toxicology and PK support
• Dermal and cardiovascular minipig models
🔬 Method Development
• LC-MS/MS matrix-effect screening
• Ligand-binding assay development
Usage Areas
- Pharma DMPK groups
- Bioanalytical CROs
- Preclinical toxicology laboratories
- Veterinary drug developers
- Research institutes
Typical Properties
- Appearance: Clear, pale-yellow liquid
- pH: 7.4 ± 0.2 (plasma, serum); about 6.5, range 6.0–7.0 (urine)
- Composition: Albumin (bovine origin) and electrolytes in buffer, K2EDTA in plasma version; urea, creatinine and salts in urine
- Biological Status: Plasma and serum contain animal-derived albumin
Storage & Stability
- Storage Temperature: 2–30 °C
- Shelf Life: 1 year for unopened bottles
- Shipping: Room temperature
- Best kept at 2–8 °C for prolonged storage and stability of the albumin components; storage at 2–30 °C is fine for short-term use
- Mix gently before use
Customization Options
- Albumin or total-protein level matched to your method
- Lithium heparin or citrate plasma versions
- Stripped-matrix alternatives
- Small aliquots for method validation
Ordering Information
BZ697 is available in standard laboratory sizes or OEM/bulk supply formats.
📄 MSDS, Technical Datasheet, and Certificate of Analysis (CoA) available upon request
📧 Email: info@biochemazone.com
🌐 Website: www.biochemazone.com
⚠️ For research and product testing only. Not for veterinary or human therapeutic use.
