Rat Fasted State Simulated Gastric Fluid BZ546
Product Code: BZ546
Manufacturer: Biochemazone
Available Pack Sizes: 100 mL, 200 mL, 500 mL, 1 L
Custom Bulk Quantities Available
Product Overview
Biochemazone Rat Fasted State Simulated Gastric Fluid BZ546 is a precisely formulated laboratory-grade synthetic gastric medium designed to replicate the physicochemical conditions of the fasted stomach environment in rats. This formulation simulates the highly acidic gastric fluid conditions typically observed in fasting physiological states, enabling reproducible in vitro and preclinical research applications.
The solution is prepared using ISO 3696 compliant high-purity water, ensuring consistent analytical performance and minimizing variability in experimental outcomes. It is widely used in pharmaceutical research, drug dissolution studies, absorption modeling, and gastrointestinal simulation studies.
This simulant reproduces key gastric parameters such as low pH, ionic strength, and chloride-rich acidic environment, making it suitable for evaluating drug stability, solubility, and degradation under fasted gastric conditions.
Key Features & Benefits
✅ pH 1.6 (Highly Acidic) – Simulates fasted gastric conditions
✅ Rat Physiological Model – Designed for preclinical gastrointestinal studies
✅ ISO 3696 Grade Water – High-purity preparation for reproducibility
✅ Gastric-Like Ionic Composition – Mimics chloride-rich stomach environment
✅ Freshly Prepared Formulation – Ensures consistency and stability
✅ Reproducible & Standardized – Reliable for comparative research
✅ Non-Biological & Safe – Free from enzymes and biological contaminants
✅ Ready-to-Use Solution – Direct application in laboratory workflows
Applications
🧪 Pharmaceutical Research
• Drug dissolution testing under fasted gastric conditions
• Formulation stability studies
• Preclinical absorption modeling
🐀 Preclinical (Rat Model) Studies
• In vitro simulation of rat gastric environment
• Pharmacokinetic and bioavailability prediction
• Gastrointestinal transit simulation
🔬 Chemical & Material Testing
• Acid stability of compounds
• Polymer and coating degradation in gastric conditions
• pH-dependent reaction profiling
🧬 Biopharmaceutical Studies
• Drug release behavior analysis
• Enteric coating performance evaluation
• Solubility profiling in acidic media
Typical Properties
- Appearance: Clear, colorless solution
• pH: 1.6 (Fasted gastric acidic condition)
• Water Grade: ISO 3696 purified water
• Ionic Composition: Chloride-rich simulated gastric electrolytes
• Viscosity: Low (physiological simulation range)
• Composition: Acidified buffered electrolyte solution
Storage & Stability
- Storage Temperature: 2–8 °C recommended
• Shelf Life: 6 to 12 months (sealed container)
• Shipping: Stable at room temperature
Customization Options
- pH adjustment (fasted/low-acid range variations)
• Ionic strength modification
• Enzyme-free or enzyme-supplemented versions (pepsin optional upon request)
• Species-specific gastric simulation tuning (rat/human/comparative models)
Ordering Information
BZ546 is available in standard laboratory sizes or OEM/bulk supply formats.
📄 MSDS, Technical Datasheet, and Certificate of Analysis (CoA) available upon request
📧 Email: info@biochemazone.com
🌐 Website: www.biochemazone.com
⚠️ For research, education, and in vitro testing only. Not for human or animal use.
