Artificial Saliva with Lactic Acid – Acidic Synthetic Saliva, pH 4.0 BZ523
Product Code: BZ523
Manufacturer: Biochemazone
Available Pack Sizes: 100 mL, 200 mL, 500 mL, 1 L
Custom Bulk Quantities Available
Product Overview
Biochemazone Artificial Saliva with Lactic Acid BZ523 is a ready-to-use, sterile acidic synthetic saliva at pH 4.0 formulated to replicate specific oral conditions. Lactic acid is the acid that plaque bacteria produce from sugars; it lowers the pH at the tooth surface below the point at which enamel starts to dissolve. BZ523 brings that acidic environment into the laboratory in a saliva-like matrix.
BZ523 is used in dental, biomedical, pharmaceutical and diagnostic research to simulate acidic oral environments: demineralization and enamel-erosion studies, caries research, corrosion and ion release of dental materials under acid challenge, and the testing of biosensors and devices at low pH. It serves as a standardized matrix for device validation, material compatibility studies and quality-control testing.
BZ523 is supplied stabilized, with a 1-year shelf life unopened; a not-stabilized, preservative-free version is available on request. The lactic acid concentration, the pH, enzymes and the pack size can be customized. For neutral saliva see Artificial Saliva or Synthetic Saliva BZ324 and BZ522 (pH 7.4); for acidic corrosion testing of dental metals see Artificial Saliva ISO 10271 and Fusayama/Meyer Artificial Saliva BZ105.
Key Features & Benefits
✅ With Lactic Acid – Acidic saliva representing the acid challenge in the mouth
✅ pH 4.0 – Customizable to the study requirement
✅ Stabilized – Preservative added to stop microbial growth; 1-year shelf life unopened
✅ Sterile & Ready to Use – No weighing, mixing or pH adjustment before the test
✅ Reproducible & Standardized – Consistent batch-to-batch composition for routine QC and inter-laboratory comparison
✅ Made in Canada – Manufactured under ISO 9001 / GMP quality systems
Applications
🦷 Demineralization & Erosion
• Enamel and dentine demineralization
• Erosion and caries research
• Remineralizing product testing
🔩 Dental Materials
• Corrosion and ion release under acid challenge
• Restoratives, adhesives and cements
• Orthodontic appliances
📟 Biosensors & Devices
• Sensor testing at low pH
• Device validation
• Material compatibility studies
🧪 Quality-Control Matrix
• Standardized acidic matrix
• Method development
• Inter-laboratory comparison
Typical Properties
- Appearance: Clear solution
- pH: 4.0 (customizable)
- Composition: Synthetic saliva with lactic acid in purified water; stabilizer added
- Format: Sterile, ready-to-use liquid, stabilized
Storage, Shelf Life & Transportation
- Storage Temperature: 2–30 °C, protected from light
- Transportation: At room temperature
- Shelf Life: 1 year (unopened)
- Preservative-Free Version: Available on request – shelf life 6 months unopened at 2–30 °C
- Powder Version Kit: Available on request – 2-year shelf life, easy to reconstitute and suitable for culture-related applications; recommended when a preservative is not required
- After Opening: Handle aseptically; close tightly after use and do not return unused material to the container
Customization Options
Customization available on request:
- Lactic acid concentration and pH
- Enzyme inclusion and modified composition
- Not-stabilized (preservative-free) version
- Powder Version Kit, custom pack sizes and bulk containers (10 L and 25 L)
Frequently Asked Questions
Why is lactic acid used?
It is the main acid formed by plaque bacteria from sugars and is the acid most often used in demineralization and caries models. A saliva with lactic acid at pH 4.0 reproduces that challenge.
Is a version without preservative available?
Yes. BZ523 is stabilized as standard; a not-stabilized, preservative-free version with a 6-month shelf life is supplied on request – state it in the order notes.
Ordering Information
BZ523 is available in standard laboratory sizes or OEM/bulk supply formats.
📄 MSDS, Technical Datasheet, and Certificate of Analysis (CoA) available upon request
📧 Email: info@biochemazone.com
🌐 Website: www.biochemazone.com
⚠️ For research, education, and in vitro testing only. Not for human or animal use.
