Artificial Fetal Interstitial Fluid (AFIF) – Synthetic Fetal Tissue Fluid for Developmental Research, pH 7.3 BZ450
Product Code: BZ450
Manufacturer: Biochemazone
Available Pack Sizes: 100 mL, 200 mL, 500 mL, 1 L
Custom Bulk Quantities Available
Product Overview
Biochemazone Artificial Fetal Interstitial Fluid (AFIF) BZ450, also called simulated fetal interstitial fluid, is a ready-to-use synthetic solution designed to replicate the properties of natural fetal interstitial fluid, at pH 7.3. It contains water, electrolytes, proteins and other biomolecules, which mimic the physical and chemical characteristics of the natural fluid. The pH of natural fetal interstitial fluid is about 7.0 to 7.5; the standard formulation is set at 7.3. Its viscosity and density are matched to the natural fluid, and it stays stable through the test.
Research laboratories use it to study the interaction between fetal interstitial fluid and the fetal tissue environment, including nutrient transport, cell growth and tissue development, and in tests that measure biomarkers in fetal interstitial fluid. It is also used to test and calibrate medical devices that interact with fetal interstitial fluid, such as diagnostic tools and laboratory equipment designed to monitor fetal development, in research on fetal health and tissue interactions, and in training in obstetrics and pediatrics, without the need for real fetal interstitial fluid.
It is supplied stabilized and has a 1-year shelf life unopened; a preservative-free version (6-month shelf life) and a dried Powder Version Kit are available on request. Because it contains protein, keep it at 2–8 °C if it is to be stored for a long time. The formulation, minerals, organic content and pH can be customized. This simulated fluid is for scientific research and in vitro use only; it is not for clinical diagnosis or treatment. For the general interstitial fluid see Simulated Interstitial Fluid (BZ254); for the subcutaneous tissue see Simulated Subcutaneous Interstitial Fluid.
Key Features & Benefits
✅ Replicates Natural fetal interstitial fluid – Water, electrolytes, proteins and other biomolecules
✅ pH 7.3 – Natural range about 7.0 to 7.5; customizable
✅ Matched Properties – Viscosity, density and pH close to the natural fluid
✅ Stabilized – Contains a preservative that stops microbial growth; 1-year shelf life unopened. Preservative-free version on request
✅ Ready to Use – No weighing, mixing or pH adjustment before the test
✅ Reproducible & Standardized – Consistent batch-to-batch composition for routine QC and inter-laboratory comparison
✅ Made in Canada – Manufactured under ISO 9001 / GMP quality systems
Applications
🔬 Developmental Research
• Nutrient transport, cell growth and tissue development
• Biomarker measurement in fetal interstitial fluid
🩺 Device Testing & Calibration
• Medical devices that interact with fetal interstitial fluid
• Diagnostic tools that monitor fetal development
🎓 Research, Training & Education
• Research on fetal health and tissue interactions
• Training in obstetrics and pediatrics without real fetal interstitial fluid
Typical Properties
- pH: 7.3 (natural range about 7.0 to 7.5; customizable)
- Composition: Water, electrolytes, proteins and other biomolecules
- Viscosity and density: Matched to the natural fluid
- Format: Ready-to-use liquid, stabilized
Storage, Shelf Life & Transportation
- Storage Temperature: 2–30 °C, protected from light
- Transportation: At room temperature
- Shelf Life: 1 year (unopened)
- Preservative-Free Version: Available on request – shelf life 6 months unopened at 2–30 °C
- Protein-Containing Product: Best kept at 2–8 °C for prolonged storage and stability; storage at 2–30 °C is fine for short-term use
- Powder Version Kit: Available on request – 2-year shelf life, easy to reconstitute and suitable for culture-related applications; recommended when a preservative is not required
- After Opening: Handle aseptically; close tightly after use and do not return unused material to the container
Customization Options
Customization available on request:
- pH adjustment to the project requirement
- Formulation, minerals and organic content
- Preservative-free (not-stabilized) version
- Powder Version Kit, custom pack sizes and bulk carboys (5 L, 10 L, 20 L)
Frequently Asked Questions
What does BZ450 contain?
Water, electrolytes, proteins and other biomolecules, at pH 7.3, with a viscosity and density matched to natural fetal interstitial fluid.
How should it be stored?
Store it at 2–30 °C; because it contains protein, 2–8 °C is best for prolonged storage. It is shipped at room temperature. Unopened, the stabilized solution has a 1-year shelf life; a preservative-free version with a 6-month shelf life and a dried Powder Version Kit with a 2-year shelf life are available on request.
Ordering Information
BZ450 is available in standard laboratory sizes or OEM/bulk supply formats.
📄 MSDS, Technical Datasheet, and Certificate of Analysis (CoA) available upon request
📧 Email: info@biochemazone.com
🌐 Website: www.biochemazone.com
⚠️ For research, education, and in vitro testing only. Not for human or animal use.
