Simulated Rabbit Plasma, Serum and Urine (Surrogate Matrices) BZ695
Product Code: BZ695
Manufacturer: Biochemazone
Available Pack Sizes: 50 mL, 100 mL, 200 mL, 500 mL
Custom Bulk Quantities Available
Product Overview
Biochemazone Simulated Rabbit Plasma, Serum and Urine BZ695 are surrogate matrices for the rabbit, a standard species in developmental toxicology, ocular and dermal studies, and antibody production. They support bioanalytical method development and standard and QC preparation without the need for blank rabbit matrix.
Plasma (K2EDTA) and serum contain albumin, globulins, glucose and electrolytes set from published rabbit reference ranges, with a pH of 7.4 ± 0.1. The urine reflects the herbivore urine of the rabbit, which is alkaline, with a pH of about 8.2 (range 7.6–8.8). Real rabbit urine is cloudy with calcium carbonate crystals; this simulant is supplied clear so it can be pipetted and analysed easily. All three are free of drugs.
The proteins are of bovine (animal) origin; no rabbit material is used. For regulated work, show parallelism with authentic matrix as required by ICH M10 and your own SOPs. Each batch is prepared with ISO 3696 compliant high-purity water under Biochemazone’s ISO 9001 / GMP quality system.
Key Features & Benefits
✅ Three Rabbit Matrices – Plasma, serum and urine
✅ pH 7.4 and About 8.2 – Blood matrices and alkaline urine
✅ Rabbit Reference Ranges – Set from published data
✅ No Rabbit Material – Consistent surrogate matrices
✅ Drug-Free – For standards and QCs
✅ Clear Urine – Easy to pipette and analyse
✅ ISO 3696 Grade Water – Prepared using high-purity laboratory water
✅ Made in Canada – Manufactured under ISO 9001 / GMP quality systems
Applications
💊 Bioanalysis & DMPK
• LC-MS/MS method development
• Standards and QC preparation
• Matrix-effect studies
🐇 Preclinical Studies
• Developmental toxicology support
• Ocular and dermal study bioanalysis
🔬 Assay Development
• Ligand-binding assay development
• Anti-drug antibody assay blanks
Usage Areas
- Pharmaceutical DMPK groups
- Contract research organisations
- Toxicology laboratories
- Bioanalytical laboratories
- Antibody producers
Typical Properties
- Appearance: Plasma and serum clear, pale yellow; urine clear, yellow
- pH: 7.4 ± 0.1 (plasma, serum); about 8.2 (urine)
- Composition: Bovine albumin and globulins, glucose and electrolytes in rabbit ranges; urine with urea, creatinine and electrolytes
- Biological Status: Contains no rabbit material; free of drugs
Storage & Stability
- Storage Temperature: 2–30 °C
- Shelf Life: 1 year for unopened bottles
- Shipping: Room temperature
- Best kept at 2–8 °C for prolonged storage and stability of the albumin and globulin components; storage at 2–30 °C is fine for short-term use
- Mix gently before use
Customization Options
- Lithium heparin or citrate plasma
- Urine with calcium carbonate sediment
- Analyte levels to your method
- Frozen aliquots
Ordering Information
BZ695 is available in standard laboratory sizes or OEM/bulk supply formats.
📄 MSDS, Technical Datasheet, and Certificate of Analysis (CoA) available upon request
📧 Email: info@biochemazone.com
🌐 Website: www.biochemazone.com
⚠️ For research and product testing only. Not for veterinary or human therapeutic use.
