Negative Synthetic Stool Matrix for Assay Development BZ609
Product Code: BZ609
Manufacturer: Biochemazone
Available Pack Sizes: 25 g, 50 g, 100 g, 250 g
Custom Bulk Quantities Available
Product Overview
Biochemazone Negative Synthetic Stool Matrix BZ609 is a pathogen-free, analyte-free faecal matrix made for developing and validating stool-based diagnostic tests. Real negative stool is hard to source, varies from donor to donor and can hide low-level targets; a synthetic matrix gives the same blank every time.
The matrix contains fibre, cellulose, lipid, salts and protein in a stool-like paste with a pH of about 6.8 (range 6.5–7.5). It is formulated without the known PCR inhibitors of real stool at high levels and is tested to confirm that spiked nucleic acid can be recovered and amplified. It is free of human DNA and of the common enteric pathogens and toxins that stool tests detect.
Laboratories spike the matrix with organisms, nucleic acids or antigens to build contrived samples for limit-of-detection, inclusivity and extraction studies. Each batch is prepared with ISO 3696 compliant high-purity water under Biochemazone’s ISO 9001 / GMP quality system.
Key Features & Benefits
✅ Negative for Common Stool Targets – Free of enteric pathogens, toxins and human DNA
✅ PCR-Compatible – Spiked nucleic acid recovery confirmed
✅ Stool-Like Paste – Behaves like stool in collection and extraction devices
✅ pH About 6.8 (Range 6.5–7.5) – Within the normal faecal range
✅ Consistent Blank – Same matrix batch after batch
✅ Small Pack Sizes – From 25 g for method development
✅ Pathogen-Free – Safe for standard laboratories
✅ Made in Canada – Manufactured under ISO 9001 / GMP quality systems
Applications
🧪 Molecular Diagnostics
• Contrived samples for multiplex GI PCR panels
• Limit-of-detection and inclusivity studies
• Nucleic-acid extraction and inhibition studies
🩺 Rapid & Immunoassay Tests
• Antigen rapid tests (for example rotavirus, norovirus, H. pylori)
• Faecal immunochemical test (FIT) development
• Calprotectin and biomarker assay matrices
🔬 Workflow Development
• Stool collection device and transport-medium testing
• Automation and liquid-handling validation
Usage Areas
- Molecular and IVD test developers
- Clinical microbiology method-validation laboratories
- Stool collection-device manufacturers
- Reference-material producers
- University research laboratories
Typical Properties
- Appearance: Brown, stool-like paste
- pH: about 6.8 (range 6.5–7.5)
- Composition: Fibre, cellulose, lipid, protein and salts; no faecal material
- Negative for: Common enteric bacteria, viruses, parasites, toxins and human DNA
- Biological Status: Non-biological
Storage & Stability
- Storage Temperature: 2–30 °C
- Shelf Life: 1 year for unopened bottles
- Shipping: Room temperature
- Best kept at 2–8 °C for prolonged storage and stability of the protein and lipid components; storage at 2–30 °C is fine for short-term use
- Mix gently before use
Customization Options
- Liquid stool matrix (diarrhoeal consistency)
- Matrix pre-diluted in transport medium
- Spiked positive matrices to customer specification (non-infectious targets)
- Custom pack sizes and bulk supply
Ordering Information
BZ609 is available in standard laboratory sizes or OEM/bulk supply formats.
📄 MSDS, Technical Datasheet, and Certificate of Analysis (CoA) available upon request
📧 Email: info@biochemazone.com
🌐 Website: www.biochemazone.com
⚠️ For research and assay development only. Not for human or animal use.
