Rat Simulated Intestinal Fluid – pH 6.8 (Physiological Intestinal Medium) BZ548
Product Code: BZ548
Manufacturer: Biochemazone
Available Pack Sizes: 100 mL, 200 mL, 500 mL, 1 L
Custom Bulk Quantities Available
Product Overview
Biochemazone Rat Simulated Intestinal Fluid BZ548 is a laboratory-formulated synthetic intestinal medium designed to replicate the physiological conditions of the rat small intestinal environment. This formulation mimics the pH, ionic composition, and buffering characteristics typically present within the intestinal tract, making it highly suitable for gastrointestinal and pharmaceutical research applications.
Prepared using ISO 3696 compliant high-purity water, this standardized formulation provides excellent reproducibility and analytical consistency for in vitro and preclinical studies. The medium is specifically engineered to simulate intestinal conditions that influence drug dissolution, solubility, permeability, stability, and absorption behavior.
BZ548 is widely used in pharmaceutical dissolution studies, intestinal permeability testing, formulation development, nutrient interaction studies, and gastrointestinal simulation research involving rat intestinal models. The formulation may also be customized with bile salts, lecithin, or enzyme components depending on specific research requirements.
Key Features & Benefits
✅ pH 6.8 (Physiological Intestinal Condition) – Simulates rat intestinal environment
✅ Rat Intestinal Simulation – Designed for gastrointestinal and preclinical studies
✅ ISO 3696 Grade Water – Prepared using high-purity laboratory water standards
✅ Physiologically Relevant Electrolyte Composition – Mimics intestinal fluid conditions
✅ Buffered Intestinal Medium – Supports reproducible dissolution and absorption studies
✅ Freshly Prepared Formulation – Ensures consistency and reliability in testing
✅ Reproducible & Standardized – Ideal for comparative analytical applications
✅ Ready-to-Use Solution – Direct laboratory application without additional preparation
Applications
🧪 Pharmaceutical Dissolution Testing
• Drug dissolution studies in intestinal conditions
• Oral formulation performance evaluation
• Controlled-release dosage form testing
🐀 Preclinical Gastrointestinal Studies
• Rat intestinal environment simulation
• Drug absorption and permeability modeling
• Gastrointestinal transit and release studies
🔬 Formulation Development
• Solubility evaluation at intestinal pH
• Stability testing in intestinal conditions
• Food interaction and excipient compatibility studies
🧬 Biopharmaceutical Research
• Intestinal absorption modeling
• Permeability and transport studies
• Comparative gastrointestinal simulation research
Typical Properties
- Appearance: Clear to slightly opalescent solution
• pH: 6.8 (Physiological intestinal condition)
• Water Grade: ISO 3696 purified water
• Ionic Composition: Intestinal electrolyte simulation profile
• Buffering Capacity: Physiologically balanced intestinal buffering system
• Viscosity: Low (modifiable upon request)
• Composition: Buffered aqueous intestinal electrolyte solution
Storage & Stability
- Storage Temperature: 2–8 °C recommended
• Shelf Life: 6 to 12 months (sealed container)
• Shipping: Stable at room temperature
Customization Options
- pH adjustment for intestinal region-specific studies
• Bile salt and lecithin supplementation
• Enzyme inclusion options (pancreatin available upon request)
• Ionic strength modification
• Species-specific intestinal simulation customization
Ordering Information
BZ548 is available in standard laboratory sizes or OEM/bulk supply formats.
📄 MSDS, Technical Datasheet, and Certificate of Analysis (CoA) available upon request
📧 Email: info@biochemazone.com
🌐 Website: www.biochemazone.com
⚠️ For research, education, and in vitro testing only. Not for human or animal use.
