Simulated Dermal Fluid – Synthetic Skin Secretion for Dermal and Skin-Contact Research, pH 5.5 BZ457
Product Code: BZ457
Manufacturer: Biochemazone
Available Pack Sizes: 100 mL, 200 mL, 500 mL, 1 L
Custom Bulk Quantities Available
Product Overview
Biochemazone Simulated Dermal Fluid BZ457, also called artificial dermal fluid, is a ready-to-use synthetic solution designed to replicate the properties of natural skin secretions, at pH 5.5. It contains water, lipids, electrolytes and proteins, which mimic the physical and chemical characteristics of the natural fluid. The pH is set at 5.5, reflecting the slightly acidic nature of healthy skin. Its viscosity and density are matched to the natural fluid, and it stays stable through the test.
Research laboratories use it to study the characteristics and behaviour of dermal fluids, including their interactions with skin tissues and barrier function, and in assays that explore dermal biomarkers. It is also used to test and calibrate medical and research devices that interact with skin fluids, such as diagnostic tools that assess skin hydration, devices that analyse skin barrier function and equipment that studies skin permeability, in research on skin physiology and dermatology, and in training in dermatology, cosmetology and skin research, without the need for actual biological samples.
It is supplied stabilized and has a 1-year shelf life unopened; a preservative-free version (6-month shelf life) and a dried Powder Version Kit are available on request. Because it contains protein, keep it at 2–8 °C if it is to be stored for a long time. The formulation, minerals, organic content and pH can be customized. This simulated fluid is for scientific research and in vitro use only; it is not for clinical diagnosis or treatment. For the fluid in the dermis see Artificial Interstitial Dermal Fluid (BZ428); for the subcutaneous tissue see Simulated Subcutaneous Interstitial Fluid.
Key Features & Benefits
✅ Replicates Natural skin secretions – Water, lipids, electrolytes and proteins
✅ pH 5.5 – The slightly acidic pH of healthy skin; customizable
✅ Matched Properties – Viscosity, density and pH close to the natural fluid
✅ Stabilized – Contains a preservative that stops microbial growth; 1-year shelf life unopened. Preservative-free version on request
✅ Ready to Use – No weighing, mixing or pH adjustment before the test
✅ Reproducible & Standardized – Consistent batch-to-batch composition for routine QC and inter-laboratory comparison
✅ Made in Canada – Manufactured under ISO 9001 / GMP quality systems
Applications
🧴 Skin Research
• Interactions of dermal fluids with skin tissues and barrier function
• Dermal biomarker assays
🩺 Device Testing & Calibration
• Diagnostic tools that assess skin hydration
• Devices that analyse skin barrier function and skin permeability
🎓 Research, Training & Education
• Research on skin physiology and dermatology
• Training in dermatology, cosmetology and skin research without biological samples
Typical Properties
- pH: 5.5 (customizable)
- Composition: Water, lipids, electrolytes and proteins
- Viscosity and density: Matched to the natural fluid
- Format: Ready-to-use liquid, stabilized
Storage, Shelf Life & Transportation
- Storage Temperature: 2–30 °C, protected from light
- Transportation: At room temperature
- Shelf Life: 1 year (unopened)
- Preservative-Free Version: Available on request – shelf life 6 months unopened at 2–30 °C
- Protein-Containing Product: Best kept at 2–8 °C for prolonged storage and stability; storage at 2–30 °C is fine for short-term use
- Powder Version Kit: Available on request – 2-year shelf life, easy to reconstitute and suitable for culture-related applications; recommended when a preservative is not required
- After Opening: Handle aseptically; close tightly after use and do not return unused material to the container
Customization Options
Customization available on request:
- pH adjustment to the project requirement
- Formulation, minerals and organic content
- Preservative-free (not-stabilized) version
- Powder Version Kit, custom pack sizes and bulk carboys (5 L, 10 L, 20 L)
Frequently Asked Questions
What does BZ457 contain?
Water, lipids, electrolytes and proteins, at pH 5.5, with a viscosity and density matched to natural skin secretions.
How should it be stored?
Store it at 2–30 °C; because it contains protein, 2–8 °C is best for prolonged storage. It is shipped at room temperature. Unopened, the stabilized solution has a 1-year shelf life; a preservative-free version with a 6-month shelf life and a dried Powder Version Kit with a 2-year shelf life are available on request.
Ordering Information
BZ457 is available in standard laboratory sizes or OEM/bulk supply formats.
📄 MSDS, Technical Datasheet, and Certificate of Analysis (CoA) available upon request
📧 Email: info@biochemazone.com
🌐 Website: www.biochemazone.com
⚠️ For research, education, and in vitro testing only. Not for human or animal use.
