Minipig / Porcine Simulated Gastric and Intestinal Fluids BZ680
Product Code: BZ680
Manufacturer: Biochemazone
Available Pack Sizes: 100 mL, 200 mL, 500 mL, 1000 mL (sets contain one bottle of each)
Custom Bulk Quantities Available
Product Overview
Biochemazone Minipig / Porcine Simulated Gastric and Intestinal Fluids BZ680 are biorelevant media for dissolution and solubility testing ahead of oral absorption studies in minipigs and pigs. The pig gut is close to the human gut in size and physiology, and minipigs are increasingly used in preclinical work, but their fluids still differ from human fluids.
Two fluids are offered, singly or as a set. The simulated gastric fluid has a pH of about 2.5 (range 1.5–4.0), reflecting the variation reported in the pig stomach, and contains pepsin of porcine origin (animal-derived). The fasted simulated intestinal fluid has a pH of about 6.5 (range 6.0–7.0) and contains bile salts and lecithin. Pig bile is rich in hyocholic and hyodeoxycholic acids, mainly glycine-conjugated; the bile salts are animal-derived.
Both fluids are based on published porcine GI data. Check the values against the data or method you use; we can adjust pH, bile salts and enzymes. Each batch is prepared with ISO 3696 compliant high-purity water under Biochemazone’s ISO 9001 / GMP quality system.
Key Features & Benefits
✅ Porcine GI Media – Gastric and fasted intestinal fluids
✅ Gastric pH About 2.5 – Range 1.5–4.0
✅ Intestinal pH About 6.5 – Range 6.0–7.0
✅ Pig Bile-Salt Profile – Based on published porcine data
✅ Singles or Sets – One or both fluids
✅ Adjustable – pH, bile salts and enzymes on request
✅ ISO 3696 Grade Water – Prepared using high-purity laboratory water
✅ Made in Canada – Manufactured under ISO 9001 / GMP quality systems
Applications
💊 Preclinical Dissolution
• Oral absorption modelling in minipigs
• Formulation screening before pig studies
• Solubility of poorly soluble drugs
🐖 Species Comparison
• Pig vs dog vs human dissolution
• PBPK model inputs
🧪 Veterinary Pharma
• Oral products for pigs
• Feed-additive release testing
Usage Areas
- Pharma formulation groups
- Preclinical and DMPK teams
- Contract research organisations
- Veterinary pharmaceutical companies
- University pharmacy departments
Typical Properties
- Appearance: Gastric fluid clear and colourless; intestinal fluid slightly turbid
- pH: gastric about 2.5 (range 1.5–4.0); intestinal about 6.5 (range 6.0–7.0)
- Composition: Gastric: salts, acid and porcine pepsin (animal-derived). Intestinal: buffer salts, bile salts (animal-derived) and lecithin
- Osmolality: Reported for each batch
Storage & Stability
- Storage Temperature: 2–30 °C
- Shelf Life: 1 year for unopened bottles
- Shipping: Room temperature
- Best kept at 2–8 °C for prolonged storage and stability of the pepsin and enzyme components; storage at 2–30 °C is fine for short-term use
- Warm to 37 °C before use
Customization Options
- Fed-state porcine media
- Enzyme-free versions for pure dissolution
- Powder versions to make up on site
- Bulk supply
Ordering Information
BZ680 is available in standard laboratory sizes or OEM/bulk supply formats.
📄 MSDS, Technical Datasheet, and Certificate of Analysis (CoA) available upon request
📧 Email: info@biochemazone.com
🌐 Website: www.biochemazone.com
⚠️ For research and product testing only. Not for veterinary or human therapeutic use.
