Artificial Brain Fluid (Simulated Brain Fluid) for Scientific Research
Artificial Brain Fluid, also known as Simulated Brain Fluid or Artificial Cerebrospinal Fluid (aCSF), is a specially formulated sterile solution that mimics the human brain and cerebrospinal fluid environment. This solution is widely utilized in scientific research and in vitro studies, ensuring that neural tissues and experiments involving brain simulations are conducted under optimal physiological conditions.
The composition is designed to maintain the ion concentration, pH value, and osmotic pressure similar to human cerebrospinal fluid (CSF), making it an ideal choice for studies involving brain slice perfusion, rat brain microdialysis, hippocampal tissue cultures, and brain trauma research.
Pack Sizes Available:
- 100 mL
- 200 mL
- 500 mL
- 1000 mL
Features and Benefits
1. Sterile and Ready to Use
It undergoes 0.22 µm sterile filtration, making it completely sterile and ready for immediate use in laboratory settings. This eliminates the need for additional processing or filtration before usage.
2. Temperature-Specific Storage and Transportation
- Storage: The solution should be stored at 2-8°C (preferably at 4°C) to maintain stability.
- Transportation: It can be transported at room temperature, ensuring easy and cost-effective logistics.
3. Maintains Physiological Balance
Unlike normal saline, which may lead to unwanted side effects, it maintains optimal ionic composition similar to that of cerebrospinal fluid, ensuring a safer and more effective solution for brain research applications.
4. Non-Clinical and Research-Oriented
This solution is strictly intended for scientific research purposes and should not be used for:
- Clinical diagnosis or treatment
- Consumption as food or medicine
- Storage in non-laboratory settings
5. Safety Precautions
For safe handling, researchers must wear:
- Lab coats
- Disposable gloves
Applications
1. Brain Slice Perfusion
It is widely used to protect intermediate neurons during brain slice perfusion, ensuring that the tissue remains viable for extended periods.
2. Brain Trauma and Injury Studies
Researchers use to treat brain trauma lesions in rats, as it helps in maintaining an optimal environment for localized irrigation and reducing secondary damage.
3. pH Balance and Oxygen Transport in Tissues
Maintaining an optimal pH balance and oxygen supply is crucial in research studies involving neural tissues, organotypic cultures, and brain function assays. It plays a critical role in preserving tissue integrity and supporting cellular activity.
4. Microdialysis Experiments
In rat brain microdialysis experiments, this fluid serves as an ideal substitute for natural cerebrospinal fluid, providing a stable environment for neurotransmitter analysis and drug testing.
How to Use
1. As a Lavage Fluid
- Used 30 minutes after an injury for lesion treatment.
- Before use, stored at 4°C, and warmed to 37°C for half an hour before application.
2. For Other Experimental Applications
- Follow specific experimental protocols to ensure proper application and effectiveness.
- Ensure sterile handling during the procedure to prevent contamination.
Storage and Handling Instructions
- Store at 2-8°C (preferably at 4°C) for stability.
- Transport at room temperature without affecting the product’s integrity.
- Do not freeze the solution, as freezing may alter its composition.
- Always use protective lab wear when handling.
Customization Options
Biochemazone™™ offers customization options for Artificial Brain Fluid:
- Standard formulation contains 0.05% preservatives (antifungal and antibacterial salts).
- Preservative-free formulations are available upon request.
- For custom orders, contact: info@biochemazone.com.
Where to Buy
Artificial Brain Fluid (BZ256) is available for purchase from Biochemazone™™. To place an order, visit: Artificial Brain Fluid Product Page.
Frequently Asked Questions (FAQs)
1. What is Artificial Brain Fluid used for?
Artificial Brain Fluid is used in scientific research and in vitro experiments to simulate the human cerebrospinal fluid environment. It is commonly used for brain slice perfusion, microdialysis, hippocampal tissue cultures, and brain trauma research.
2. Can Artificial Brain Fluid be used for clinical purposes?
No, Artificial Brain Fluid is strictly for research purposes only. It cannot be used for clinical diagnosis or treatment, nor for food or medicinal applications.
3. What is the storage requirement for Artificial Brain Fluid?
It should be stored at 2-8°C (ideally at 4°C) and transported at room temperature. Freezing is not recommended.
4. How should Artificial Brain Fluid be handled safely?
Always use lab coats and disposable gloves when handling the solution to maintain sterile conditions and ensure safety.
5. Is a preservative-free version available?
Yes, Biochemazone™™ offers preservative-free Artificial Brain Fluid upon request. Contact info@biochemazone.com for customization.
6. Where can I purchase Artificial Brain Fluid?
You can buy Artificial Brain Fluid (BZ256) directly from Biochemazone™™. Visit the official product page at Biochemazone™ Artificial Brain Fluid to place an order.
Artificial Brain Fluid is a crucial component in neuroscientific research, offering a reliable and sterile solution for maintaining brain tissue viability in experimental settings. Whether for brain slice perfusion, microdialysis, or brain injury research, this solution provides an optimal environment for conducting accurate and reproducible studies. Choose Biochemazone™™ for high-quality artificial fluids tailored to your research needs.
