Fasted State Simulated Gastric Fluid (FaSSGF) Dried Powder BZ553
Product Code: BZ553
Manufacturer: Biochemazone
Available Pack Sizes for Making: 100 mL, 200 mL, 500 mL, 1000 mL
Custom Bulk Quantities Available
Product Overview
Biochemazone Fasted State Simulated Gastric Fluid (FaSSGF) Dried Powder BZ553 is a laboratory-formulated powdered medium designed to simulate the physiological composition and biorelevant conditions of the human stomach under fasted-state conditions. This dry-format formulation allows convenient storage, transportation, and preparation of fresh simulated gastric fluid prior to experimental use.
The formulation is specifically developed to mimic the gastric environment encountered in the upper gastrointestinal tract during fasting, including low pH conditions, gastric electrolyte composition, enzymatic activity (pepsin-like environment), and physiological surface activity. This makes it highly suitable for pharmaceutical dissolution studies, oral drug delivery research, stability testing, and biopharmaceutical evaluation applications.
Prepared using high-purity analytical-grade components, this standardized dried powder formulation provides excellent reproducibility and consistency for in vitro and preclinical studies. Upon reconstitution with purified water, the solution simulates gastric fluid conditions relevant to drug disintegration, solubility behavior, acid stability, and early-stage gastrointestinal transit behavior.
BZ553 is widely used in oral drug formulation development, dissolution and release testing, bioaccessibility studies, gastric stability assessment, and biorelevant media testing. The formulation contains no preservatives and may also be customized for specific pH ranges, enzyme activity levels, surfactant systems, or specialized gastrointestinal simulation requirements depending on research applications.
Key Features & Benefits
✅ Simulated Fasted-State Gastric Environment – Designed to mimic physiological gastric fluid conditions during fasting
✅ Dried Powder Format – Convenient storage and preparation of fresh media
✅ Preservative-Free Formulation – Suitable for sensitive research applications
✅ Biorelevant Composition – Mimics gastric electrolyte and enzymatic environment
✅ Physiological Low pH Simulation – Suitable for gastric dissolution and stability studies
✅ Reproducible & Standardized – Ideal for comparative laboratory applications
✅ High-Purity Components – Prepared using analytical-grade raw materials
✅ Freshly Reconstituted Medium – Enhances experimental consistency and stability
✅ Ready-to-Prepare Formulation – Simple reconstitution for laboratory use
Applications
🧪 Pharmaceutical & Drug Delivery Research
- Oral drug dissolution and release studies
• Acid stability and degradation testing
• Solubility and bioavailability enhancement testing
Preclinical & Biomedical Studies
- Gastric environment simulation
• Permeability and absorption assessment
• Controlled-release oral formulation studies
🔬 Biopharmaceutical & Analytical Research
- Biorelevant dissolution testing
• Supersaturation and precipitation studies in gastric conditions
• Comparative formulation performance evaluation
🧬 Drug Development & Formulation Studies
- pH-dependent oral formulation assessment
• BCS classification support studies
• Acid-labile drug evaluation
Typical Properties
- Appearance: Off-white to white free-flowing powder
• Reconstituted Appearance: Clear to slightly opalescent solution
• pH (after reconstitution): Physiological fasted-state gastric pH range
• Solubility: Water soluble upon reconstitution
• Composition: Buffered gastric electrolyte and enzymatic (pepsin-simulated) formulation, Pathogen Free
• Preservatives: None
• Buffering Capacity: Physiologically balanced gastric buffering system
• Format: Dried powder preparation
Storage & Stability
- Storage Temperature: 2–30 °C recommended
• Shelf Life: 12–24 months (sealed container)
• Shipping: Stable at room temperature
Customization Options
- pH adjustment for specific gastrointestinal studies
• Customized electrolyte and enzyme activity levels
• Surfactant and gastric composition modifications
• Fed-state simulation modifications available upon request
• Species-specific or study-specific gastric simulation customization
Ordering Information
BZ553 is available in standard laboratory sizes or OEM/bulk supply formats.
📄 MSDS, Technical Datasheet, and Certificate of Analysis (CoA) available upon request
📧 Email: info@biochemazone.com
🌐 Website: Biochemazone
⚠️ For research, education, and in vitro testing only. Not for human or animal use
