Endometrial Simulation Medium (ESM) – Synthetic Endometrial Medium for Reproductive Research, pH 7.2 BZ409
Product Code: BZ409
Manufacturer: Biochemazone
Available Pack Sizes: 100 mL, 200 mL, 500 mL, 1 L
Custom Bulk Quantities Available
Product Overview
Biochemazone Endometrial Simulation Medium (ESM) BZ409, also called synthetic endometrial simulation medium, is a sterile, ready-to-use medium at pH 7.2 that simulates the environment of the human endometrium, the lining of the uterus. It is designed to give suitable conditions for the growth and differentiation of endometrial cells and to support cell functions such as proliferation, adhesion and hormone response.
ESM is used in reproductive biology and related research: to culture embryos under conditions like those of the uterus, to study how endometrial cells respond to hormones and drugs, to model diseases such as endometriosis and endometrial cancer in a controlled environment, and to support the growth of endometrial tissue for regenerative medicine. It is also used by diagnostic companies for testing biosensor devices, and by laboratories as a matrix for quality control preparations.
It is supplied stabilized and has a 1-year shelf life unopened; a preservative-free version (6-month shelf life) and a dried Powder Version Kit are available on request. For cell and embryo culture, order the preservative-free version or the Powder Version Kit, which is prepared on site with sterile water. The formulation, minerals, organic content and pH can be customized. This simulated fluid is for scientific research and in vitro use only; it is not for clinical diagnosis or treatment. For the secretions of the endometrium see Simulated Endometrial Secretions (BZ419); for the fluid of the uterus see Simulated Uterine Fluid (BZ318).
Key Features & Benefits
✅ Simulates the Endometrial Environment – Conditions for the growth and differentiation of endometrial cells
✅ pH 7.2 – Customizable to the project requirement
✅ No Patient Samples – The same composition in every batch
✅ Stabilized – Contains a preservative that stops microbial growth; 1-year shelf life unopened. Preservative-free version on request
✅ Sterile & Ready to Use – No weighing, mixing or pH adjustment before the test
✅ Reproducible & Standardized – Consistent batch-to-batch composition for routine QC and inter-laboratory comparison
✅ Made in Canada – Manufactured under ISO 9001 / GMP quality systems
Applications
🧫 IVF & Embryo Culture
• Culture of embryos under conditions like those of the uterus
🔬 Endometrial Research
• Behaviour of endometrial cells
• Response to hormones and drugs
🧬 Disease Modelling
• Endometriosis
• Endometrial cancer
🧪 Tissue Engineering & QC
• Growth of endometrial tissue for regenerative medicine
• Matrix for quality control preparations
• Testing of biosensor devices
Typical Properties
- Appearance: Clear solution
- pH: 7.2 (customizable)
- Composition: Endometrial simulation medium; minerals and organic content customizable
- Format: Sterile, ready-to-use liquid, stabilized
Storage, Shelf Life & Transportation
- Storage Temperature: 2–30 °C, protected from light
- Transportation: At room temperature
- Shelf Life: 1 year (unopened)
- Preservative-Free Version: Available on request – shelf life 6 months unopened at 2–30 °C
- Powder Version Kit: Available on request – 2-year shelf life, easy to reconstitute and suitable for culture-related applications; recommended when a preservative is not required
- After Opening: Handle aseptically; close tightly after use and do not return unused material to the container
Customization Options
Customization available on request:
- pH adjustment to the project requirement
- Formulation, minerals and organic content
- Preservative-free (not-stabilized) version
- Powder Version Kit, custom pack sizes and bulk carboys (5 L, 10 L, 20 L)
Frequently Asked Questions
Which version should I order for culture work?
The preservative-free version, or the Powder Version Kit prepared on site with sterile water. The standard stabilized version contains a preservative and suits device, materials and method work.
How long does the solution keep?
Unopened, the stabilized solution has a 1-year shelf life at 2–30 °C. A preservative-free version with a 6-month shelf life and a dried Powder Version Kit with a 2-year shelf life are available on request.
Ordering Information
BZ409 is available in standard laboratory sizes or OEM/bulk supply formats.
📄 MSDS, Technical Datasheet, and Certificate of Analysis (CoA) available upon request
📧 Email: info@biochemazone.com
🌐 Website: www.biochemazone.com
⚠️ For research, education, and in vitro testing only. Not for human or animal use.
